Retraction: “The Role of the Extracellular Matrix Protein Mindin in Airway Response to Environmental Airways Injury”
نویسندگان
چکیده
This article is being retracted at the request of the authors because of concerns about the accuracy of the initial data from the animal physiology laboratory at Duke University. The authors re-exported source data from the animal ventilator (FlexiVent) and compared the output with the raw data originally received from the animal pulmonary physiology laboratory. The results from these initial comparisons suggested potential inconsistencies in the data, so the authors requested that an independent laboratory replicate the experiments of animal airway physiology presented in Figure 1 and Figure 4. The results of the replicated experiments validated the originally reported central role of mindin in airway hyper-responsiveness after exposure to either lipopolysaccharide (LPS) or ozone.
منابع مشابه
The Role of the Extracellular Matrix Protein Mindin in Airway Response to Environmental Airways Injury
BACKGROUND Our previous work demonstrated that the extracellular matrix protein mindin contributes to allergic airways disease. However, the role of mindin in nonallergic airways disease has not previously been explored. OBJECTIVES We hypothesized that mindin would contribute to airways disease after inhalation of either lipopolysaccharide (LPS) or ozone. METHODS We exposed C57BL/6J and min...
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عنوان ژورنال:
دوره 124 شماره
صفحات -
تاریخ انتشار 2016